Evolution in random fitness landscapes: the infinite sites model
نویسندگان
چکیده
منابع مشابه
Evolution in random fitness landscapes: the infinite sites model
We consider the evolution of an asexually reproducing population in an uncorrelated random fitness landscape in the limit of infinite genome size, which implies that each mutation generates a new fitness value drawn from a probability distribution g(w). This is the finite population version of Kingman’s house of cards model [J.F.C. Kingman, J. Appl. Probab. 15, 1 (1978)]. In contrast to Kingman...
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One of the most fundamental concepts of evolutionary dynamics is the ‘fixation’ probability, i.e. the probability that a gene spreads through the whole population. Most natural communities are geographically structured into habitats exchanging individuals among themselves. The topology of the migration patterns is believed to influence the spread of a new mutant, but no general analytical resul...
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We formalize the problem of recovering the evolutionary history of a set of genomes that are related to an unseen common ancestor genome by operations of speciation, deletion, insertion, duplication, and rearrangement of segments of bases. The problem is examined in the limit as the number of bases in each genome goes to infinity. In this limit, the chromosomes are represented by continuous cir...
متن کاملFitness landscapes and evolution
The concept of fitness is introduced, and a simple derivation of the Fundamental Theorem of Natural Selection (which states that the average fitness of a population increases if its variance is nonzero) is given. After a short discussion of the adaptative walk model, a short review is given of the quasispecies approach to molecular evolution and to the error threshold. The relevance of flat fit...
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Evolution in changing environments is an important, but little studied aspect of the theory of evolution. The idea of adaptive walks in fitness landscapes has triggered a vast amount of research and has led to many important insights about the progress of evolution. Nevertheless, the small step to time-dependent fitness landscapes has most of the time not been taken. In this work, some elements...
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ژورنال
عنوان ژورنال: Journal of Statistical Mechanics: Theory and Experiment
سال: 2008
ISSN: 1742-5468
DOI: 10.1088/1742-5468/2008/04/p04014